Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207412 | 0.89 | TLR7 (0.43) | TLR7ADORA2AADORA1MAPK1ALDH1A1 | |
| SCHEMBL7204696 | 0.85 | ADORA2A (0.61) | TLR7ADORA2AADORA1MAPK1KDM4E | |
| SCHEMBL5730944 | 0.83 | TLR7 (0.55) | TLR7ADORA2AADORA1MAPK1KDM4E | |
| SCHEMBL7212493 | 0.82 | ADORA2A (0.47) | TLR7ADORA2AADORA1MAPK1PNP | |
| SCHEMBL7204709 | 0.82 | ADORA2A (0.47) | TLR7ADORA2AADORA1MAPK1ALDH1A1 | |
| SCHEMBL2060321 | 0.81 | ADORA2A (0.46) | TLR7ADORA2AADORA1MAPK1KDM4E | |
| SCHEMBL14944613 | 0.81 | ADORA2A (0.46) | TLR7ADORA2AADORA1MAPK1PNP | |
| SCHEMBL7209948 | 0.81 | TSHR (0.52) | TLR7ADORA2AADORA1MAPK1ALDH1A1 | |
| SCHEMBL10174942 | 0.81 | TLR7 (0.49) | TLR7ADORA2AADORA1KDM4EALDH1A1 | |
| SCHEMBL19370095 | 0.80 | ADORA2A (0.45) | TLR7ADORA2AADORA1MAPK1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |