Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LSS | P48449 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209669 | 0.87 | LSS (0.58) | CNR2LMNAALDH1A1LSSTHRB | |
| SCHEMBL7203923 | 0.87 | CNR2 (0.47) | CNR2LMNAALDH1A1THRBTP53 | |
| SCHEMBL7205305 | 0.87 | HPGD (0.47) | CNR2LMNAALDH1A1THRBTP53 | |
| SCHEMBL7211573 | 0.86 | LSS (0.57) | CNR2LMNAALDH1A1LSSTHRB | |
| SCHEMBL7204701 | 0.82 | LSS (0.70) | CNR2LSS | |
| SCHEMBL7204697 | 0.82 | LSS (0.70) | CNR2LSS | |
| SCHEMBL7209476 | 0.81 | CA1 (0.39) | CNR2LMNAALDH1A1LSSCA1 | |
| SCHEMBL4803916 | 0.79 | LSS (0.47) | LSSMEN1KMT2A | |
| SCHEMBL4803921 | 0.79 | LSS (0.47) | LSSMEN1KMT2A | |
| SCHEMBL7203719 | 0.79 | LSS (0.71) | CNR2LMNAALDH1A1LSSTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |