SCHEMBL7204777

SCHEMBL7204777

CONc1nc(N)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.59
LMNA P02545 1/20 0.59
TP53 P04637 1/20 0.59
HTT P42858 1/20 0.59
PDE4D Q08499 1/20 0.59
PDE3A Q14432 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
ADRB1 P08588 1/20 0.53
DNMT1 P26358 1/20 0.53
CYP1A2 P05177 1/20 0.53
HBB P68871 1/20 0.53
ADORA3 P0DMS8 1/20 0.53
ADORA1 P30542 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8088381 1.00 PNP (0.59) PNPLMNATP53HTTPDE4D
SCHEMBL27093634 1.00 PNP (0.59) PNPLMNATP53HTTPDE4D
SCHEMBL5983833 0.89 ADORA3 (0.67) PNPLMNATP53HTTPDE4D
SCHEMBL5983838 0.89 ADORA3 (0.67) PNPLMNATP53HTTPDE4D
SCHEMBL23352546 0.85 PNP (0.62) PNPLMNATP53HTTPDE4D
SCHEMBL657819 0.85 PNP (0.62) PNPLMNATP53HTTPDE4D
SCHEMBL21162582 0.85 PNP (0.62) PNPLMNATP53HTTPDE4D
SCHEMBL29502677 0.85 PNP (0.62) PNPLMNATP53HTTPDE4D
SCHEMBL17521211 0.85 PNP (0.62) PNPLMNATP53HTTPDE4D
SCHEMBL9141685 0.85 PNP (0.62) PNPLMNATP53HTTPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4323517-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES AND PROCESSES RELATED TO ALTERATION OF THEIR PHYSICOCHEMICAL CHARACTERISTICS Sixfold Bioscience Ltd. (GB) 2024-02-21 EP claimed
EP-4323517-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES AND PROCESSES RELATED TO ALTERATION OF THEIR PHYSICOCHEMICAL CHARACTERISTICS Sixfold Bioscience Ltd. (GB) 2024-02-21 EP disclosed
US-9670540-B2 Methods and devices for DNA sequencing and molecular diagnostics CORNELL UNIVERSITY (US) 2017-06-06 US disclosed
US-20150099642-A1 METHODS AND DEVICES FOR DNA SEQUENCING AND MOLECULAR DIAGNOSTICS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2015-04-09 US disclosed
WO-2013012440-A2 METHODS AND DEVICES FOR DNA SEQUENCING AND MOLECULAR DIAGNOSTICS CORNELL UNIVERSITY (US) 2013-01-24 WO disclosed
EP-1151093-A4 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORP (US) 2003-01-08 EP disclosed
WO-2000046366-A9 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORP (US) 2002-02-14 WO disclosed
EP-1151093-A1 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORPORATION (US) 2001-11-07 EP disclosed
EP-0866796-B1 IMPROVEMENTS IN OR RELATING TO MUTAGENESIS OF NUCLEIC ACIDS AMERSHAM PHARM BIOTECH UK LTD (GB) 2000-11-29 EP disclosed
WO-2000046366-A1 ISOLATION OF NUCLEIC ACID MOLECULES INVITROGEN CORPORATION (US) 2000-08-10 WO disclosed