Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204813 | 1.00 | HSD11B1 (0.34) | HSD11B1CA12CA1CA2CA9 | |
| SCHEMBL7207150 | 0.86 | EPHX2 (0.37) | HSD11B1CA12CA1CA2CA9 | |
| SCHEMBL7207158 | 0.86 | EPHX2 (0.37) | HSD11B1CA12CA1CA2CA9 | |
| SCHEMBL4798099 | 0.85 | HSD11B1 (0.35) | HSD11B1LSSASGR1HDAC1HDAC2 | |
| SCHEMBL4798104 | 0.85 | HSD11B1 (0.35) | HSD11B1LSSASGR1HDAC1HDAC2 | |
| SCHEMBL4805312 | 0.84 | LSS (0.36) | HSD11B1LSSASGR1HDAC1HDAC2 | |
| SCHEMBL4805308 | 0.84 | LSS (0.36) | HSD11B1LSSASGR1HDAC1HDAC2 | |
| SCHEMBL4797914 | 0.84 | LSS (0.36) | HSD11B1LSSASGR1HDAC1HDAC2 | |
| SCHEMBL4805763 | 0.84 | LSS (0.36) | HSD11B1LSSASGR1HDAC1HDAC2 | |
| SCHEMBL4805767 | 0.84 | LSS (0.36) | HSD11B1LSSASGR1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |