Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 6/20 | 0.66 |
| ▸ | FPR1 | P21462 | 5/20 | 0.66 |
| ▸ | NMBR | P28336 | 10/20 | 0.59 |
| ▸ | GRPR | P30550 | 9/20 | 0.59 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193483 | 0.82 | FPR2 (0.54) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL7849159 | 0.80 | FPR2 (0.68) | FPR2FPR1NMBRPOLBCTDSP1 | |
| SCHEMBL6250550 | 0.80 | NMBR (0.71) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL6250547 | 0.80 | NMBR (0.71) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL6810079 | 0.79 | NMBR (0.58) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL6252362 | 0.79 | NMBR (0.57) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL6250069 | 0.78 | NMBR (0.73) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL7138683 | 0.78 | NMBR (0.66) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL6250000 | 0.78 | NMBR (0.70) | FPR2FPR1NMBRGRPRAGTR1 | |
| SCHEMBL7678106 | 0.78 | FPR2 (0.51) | FPR2FPR1NMBRGRPRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333824-A2 | TREATMENT OF SEXUAL DYSFUNCTION | Warner-Lambert Company LLC (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002040008-A2 | TREATMENT OF SEXUAL DYSFUNCTION WITH NON PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-23 | — | — | WO | disclosed |