Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 16/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205134 | 1.00 | LSS (0.61) | LSSACHEMGLLFPR3FPR2 | |
| SCHEMBL7210998 | 0.99 | LSS (0.60) | LSSACHEMGLL | |
| SCHEMBL7210999 | 0.99 | LSS (0.60) | LSSACHEMGLL | |
| SCHEMBL4797244 | 0.95 | LSS (0.60) | LSSACHE | |
| SCHEMBL4797247 | 0.95 | LSS (0.60) | LSSACHE | |
| SCHEMBL7204037 | 0.90 | LSS (0.74) | LSSACHE | |
| SCHEMBL7206527 | 0.90 | LSS (0.74) | LSSACHE | |
| SCHEMBL7211557 | 0.89 | LSS (0.77) | LSSACHE | |
| SCHEMBL7203223 | 0.89 | LSS (0.77) | LSSACHE | |
| SCHEMBL7210419 | 0.89 | LSS (0.77) | LSSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | claimed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | claimed |
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |