SCHEMBL7210419

SCHEMBL7210419

CCCCCN(C)CCCCCC1CCC(N(C)C(=O)Oc2ccc(C(F)(F)F)cc2)CC1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LSS P48449 17/20 0.77
ACHE P22303 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7203223 1.00 LSS (0.77) LSSACHE
SCHEMBL7211557 1.00 LSS (0.77) LSSACHE
SCHEMBL7203457 0.99 LSS (0.75) LSSACHE
SCHEMBL4807833 0.95 LSS (0.75) LSSACHE
SCHEMBL4807826 0.95 LSS (0.75) LSSACHE
SCHEMBL7205473 0.89 LSS (0.65) LSS
SCHEMBL7205476 0.89 LSS (0.65) LSS
SCHEMBL7205134 0.89 LSS (0.61) LSSACHE
SCHEMBL7205131 0.89 LSS (0.61) LSSACHE
SCHEMBL7204037 0.89 LSS (0.74) LSSACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1311475-A1 NOVEL AMINOCYCLOHEXANE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-05-21 EP claimed
WO-2002014267-A1 NOVEL AMINOCYCLOHEXANE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2002-02-21 WO claimed
EP-1311475-A1 NOVEL AMINOCYCLOHEXANE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-05-21 EP disclosed
WO-2002014267-A1 NOVEL AMINOCYCLOHEXANE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2002-02-21 WO disclosed