Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978972 | 0.85 | — | — | |
| SCHEMBL9039250 | 0.74 | GAA (0.35) | — | |
| SCHEMBL7426721 | 0.73 | — | — | |
| SCHEMBL18989643 | 0.72 | — | — | |
| SCHEMBL3945997 | 0.71 | — | — | |
| SCHEMBL9038111 | 0.71 | RAB9A (0.45) | — | |
| SCHEMBL3939674 | 0.71 | MAP3K7 (0.33) | MAP3K7TAB1 | |
| SCHEMBL14889066 | 0.70 | — | — | |
| SCHEMBL12489591 | 0.69 | — | — | |
| SCHEMBL3938829 | 0.69 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1045833-A1 | 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS | PFIZER INC. (US) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999035130-A1 | 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS | PFIZER PHARMACEUTICALS INC. (JP) | 1999-07-15 | — | — | WO | disclosed |