Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12890740 | 0.88 | KDM1A (0.50) | KDM1AMAOAMAOBCYP1A2SIRT2 | |
| SCHEMBL14315379 | 0.82 | SMN1; SMN2 (0.50) | KDM1AMAOAMAOBCYP1A2SIRT2 | |
| SCHEMBL25228350 | 0.81 | KDM1A (0.45) | KDM1AMAOAMAOBCYP1A2SIRT2 | |
| SCHEMBL2458989 | 0.79 | SMN1; SMN2 (0.54) | KDM1AMAOAMAOBCYP1A2SIRT2 | |
| SCHEMBL1094558 | 0.79 | KDM1A (0.54) | KDM1AMAOAMAOBCYP1A2PDE10A | |
| SCHEMBL6703238 | 0.79 | KDM1A (0.54) | KDM1AMAOAMAOBCYP1A2PDE10A | |
| SCHEMBL2461025 | 0.78 | CASR (0.52) | KDM1AMAOAMAOBCYP1A2PDE10A | |
| SCHEMBL3345872 | 0.78 | CASR (0.52) | KDM1AMAOAMAOBCYP1A2PDE10A | |
| SCHEMBL22779486 | 0.76 | KDM1A (0.51) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL6154350 | 0.76 | KDM1A (0.51) | KDM1AMAOAMAOBCYP1A2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343798-A1 | 6-O-CARBAMOYL KETOLIDE DERIVATIVES OF ERYTHROMYCIN USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002046204-A1 | 6-0-CARBAMOYL KETOLIDE DERIVATIVES OF ERYTHROMYCIN USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-06-13 | — | — | WO | disclosed |