Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703238 | 0.83 | KDM1A (0.54) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL28659112 | 0.83 | KDM1A (0.48) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL6154350 | 0.80 | KDM1A (0.51) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL4815367 | 0.79 | PDGFRB (0.50) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL1094558 | 0.79 | KDM1A (0.54) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL28879876 | 0.79 | CYP1A2 (0.59) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL19953602 | 0.78 | KDM1A (0.63) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL3820110 | 0.77 | CYP1A2 (0.52) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL4819797 | 0.77 | PDGFRB (0.47) | KDM1AMAOAMAOBCYP1A2PDGFRB | |
| SCHEMBL894052 | 0.77 | MAOA (0.51) | KDM1AMAOAMAOBCYP1A2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512867-B1 | NOVEL COMPOUNDS | DSM IP ASSETS BV (NL) | 2020-12-16 | — | — | EP | disclosed |