Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943109 | 0.73 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1GAAHTT | |
| SCHEMBL4629536 | 0.73 | KCNH2 (0.42) | MAPTKCNH2CNR1TLR8CNR2 | |
| SCHEMBL10760575 | 0.72 | KCNH2 (0.44) | MAPTKCNH2CNR1TLR8CNR2 | |
| SCHEMBL2254077 | 0.72 | KCNH2 (0.44) | MAPTKCNH2CNR1TLR8CNR2 | |
| SCHEMBL5750528 | 0.72 | KCNH2 (0.44) | MAPTKCNH2CNR1TLR8CNR2 | |
| SCHEMBL292073 | 0.72 | KCNH2 (0.44) | MAPTKCNH2CNR1TLR8CNR2 | |
| SCHEMBL11754126 | 0.72 | KCNH2 (0.44) | MAPTKCNH2CNR1TLR8CNR2 | |
| SCHEMBL114219 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP1A2HPGDCYP2C19 | |
| SCHEMBL7565940 | 0.71 | TRPM4 (0.38) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7950716 | 0.70 | ALDH1A1 (0.33) | KDM4EALDH1A1GAACYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610891-B1 | Reduces degradation or decomposition of catalyst | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-08-26 | — | — | US | disclosed |