Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310414 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1RNPEPSLC7A5 | |
| SCHEMBL2328816 | 0.94 | — | — | |
| SCHEMBL23846021 | 0.83 | TSHR (0.44) | ALDH1A1TSHRMAPK1RNPEPSLC7A5 | |
| SCHEMBL17274592 | 0.83 | TSHR (0.44) | ALDH1A1TSHRMAPK1RNPEPSLC7A5 | |
| SCHEMBL31380967 | 0.83 | TSHR (0.44) | ALDH1A1TSHRMAPK1RNPEPSLC7A5 | |
| SCHEMBL19819960 | 0.83 | TSHR (0.44) | ALDH1A1TSHRMAPK1RNPEPSLC7A5 | |
| SCHEMBL599901 | 0.79 | TSHR (0.47) | ALDH1A1TSHRMAPK1RNPEPSLC7A5 | |
| SCHEMBL8374257 | 0.77 | — | — | |
| SCHEMBL8375357 | 0.77 | — | — | |
| SCHEMBL21830468 | 0.75 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1RNPEPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903350-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-0518238-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0903350-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5508421-A | Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5362882-A | Intermediates for dyes for polyesters, images for heat sensitive elements and electrography | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0518238-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |