⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571392 | 0.74 | — | — | |
| SCHEMBL17975570 | 0.67 | — | — | |
| Hydroxyguanidine SCHEMBL116225 | 0.64 | — | — | |
| Hydroxyurea SCHEMBL31177136 | 0.60 | — | — | |
| SCHEMBL2268990 | 0.60 | — | — | |
| Hydroxyguanidine SCHEMBL7265255 | 0.60 | — | — | |
| Hydroxyguanidine SCHEMBL5262447 | 0.60 | — | — | |
| SCHEMBL2268985 | 0.60 | — | — | |
| SCHEMBL2268982 | 0.60 | — | — | |
| SCHEMBL11199953 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599943-B1 | Preventive treatment, related to the radical generating nature of the xanthine dehydrogenase/xanthine oxidase | WAPHARM AB (SE) | 2003-07-29 | — | — | US | disclosed |
| WO-2000035952-A2 | COMPOUNDS FOR CONTROL OF EATING, GROWTH AND BODY WEIGHT | MELACURE THERAPEUTICS AB (SE) | 2000-06-22 | — | — | WO | disclosed |
| EP-1007025-A1 | USE OF HYDROXYGUANIDINES | Wa Pharm AB (SE) | 2000-06-14 | — | — | EP | disclosed |
| WO-1998023267-A1 | USE OF HYDROXYGUANIDINES | WAPHARM AB (SE) | 1998-06-04 | — | — | WO | disclosed |