Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206271 | 0.93 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL7209704 | 0.90 | EDNRA (0.68) | EDNRAEDNRB | |
| SCHEMBL7205085 | 0.90 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL7205102 | 0.88 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL7206055 | 0.88 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL7206619 | 0.88 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL7205231 | 0.88 | EDNRA (0.77) | EDNRAEDNRB | |
| SCHEMBL7208928 | 0.87 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL8326900 | 0.85 | EDNRA (0.82) | EDNRAEDNRB | |
| SCHEMBL7204657 | 0.85 | EDNRA (0.81) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852226-B1 | PYRIMIDINE DERIVATIVES | KOWA CO (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5883092-A | Pyrimidine derivatives as endothelin antagonists | KOWA CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0852226-A1 | PYRIMIDINE DERIVATIVES | KOWA CO. LTD. (JP) | 1998-07-08 | — | — | EP | disclosed |