Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201208 | 1.00 | CNR2 (0.56) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL6895598 | 1.00 | CNR2 (0.56) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7095958 | 1.00 | CNR2 (0.56) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7092691 | 0.98 | CNR2 (0.57) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7092601 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7091892 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7092599 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7091255 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7097469 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7096609 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605645-B2 | Such as 1,15-di(cyclopropylmethylamino)-8-benzyl-4,8,12-triazapentadecane; carcinostatic action | RIKEN (JP) | 2003-08-12 | — | — | US | disclosed |