Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.49 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206014 | 1.00 | CNR2 (0.56) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7201208 | 1.00 | CNR2 (0.56) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7095958 | 1.00 | CNR2 (0.56) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7092691 | 0.98 | CNR2 (0.57) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7092601 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7091892 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7092599 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7091255 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7097469 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A | |
| SCHEMBL7096609 | 0.97 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38417-E1 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2004-02-03 | — | — | US | disclosed |
| US-20020094990-A1 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | BERGERON RAYMOND J (US) | 2002-07-18 | — | — | US | disclosed |
| US-6362232-B1 | SKIN DISORERS; INSECTICIDES | BERGERON RAYMOND J (US) | 2002-03-26 | — | — | US | disclosed |
| US-6147262-A | ANTIPROLIFERATIVE AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2000-11-14 | — | — | US | disclosed |
| US-6034139-A | POLYAMINE COMPOUND | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5866613-A | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5827894-A | ANTITUMOR AGENTS, ANTIGROWTH AGENTS FOR TREATMENT OF PSORIASIS, INSECTICIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| US-5681837-A | MOSQUITO INSECTICIDAL COMPOSITION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| US-5679682-A | ADMINISTERING SPERMINE DERIVATIVE; MOSQUITO GROWTH CONTROLLER | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5455277-A | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5342945-A | Bis-hexahydropyrimidinylakyl compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 1994-08-30 | — | — | US | disclosed |
| US-5091576-A | Antipsoriasis, insecticides | UNIVERSITY OF FLORIDA (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0349224-A2 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | THE UNIVERSITY OF FLORIDA (US) | 1990-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094990-A1 | Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives | SRM, SMS, SMOX | CNR2 3306/4885HTT 264/4885LMNA 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.