Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206298 | 1.00 | HRH3 (0.52) | HRH3SMN1; SMN2KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7201657 | 0.99 | HRH3 (0.51) | HRH3SMN1; SMN2KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7201662 | 0.99 | HRH3 (0.51) | HRH3SMN1; SMN2KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8482881 | 0.83 | HRH3 (0.46) | HRH3KDM4ELTA4HALDH1A1 | |
| SCHEMBL3064562 | 0.82 | POLB (0.50) | HRH3KDM4ERAB9ALTA4HALDH1A1 | |
| SCHEMBL3556745 | 0.82 | POLB (0.50) | HRH3KDM4ERAB9ALTA4HALDH1A1 | |
| SCHEMBL3064563 | 0.82 | POLB (0.50) | HRH3KDM4ERAB9ALTA4HALDH1A1 | |
| Hydrochloric Acid SCHEMBL3067120 | 0.81 | POLB (0.49) | HRH3KDM4ERAB9ALTA4HALDH1A1 | |
| Hydrochloric Acid SCHEMBL7218972 | 0.81 | POLB (0.49) | HRH3KDM4ERAB9ALTA4HALDH1A1 | |
| Hydrochloric Acid SCHEMBL3067119 | 0.81 | POLB (0.49) | HRH3KDM4ERAB9ALTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045387-A1 | PHARMACEUTICAL COMPOSITION WITH COMBINED ACTIVE AGENTS CONTAINING METFORMIN AND A HYDROXYLAMINE DERIVATIVE | BIOREX KUTATÓ ÉS FEJLESZTÖ RT. (HU) | 2003-06-05 | — | — | WO | claimed |
| WO-2003045387-A1 | PHARMACEUTICAL COMPOSITION WITH COMBINED ACTIVE AGENTS CONTAINING METFORMIN AND A HYDROXYLAMINE DERIVATIVE | BIOREX KUTATÓ ÉS FEJLESZTÖ RT. (HU) | 2003-06-05 | — | — | WO | disclosed |