Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211209 | 0.93 | HTR2A (0.44) | HTR2AHRH1RETCDK8CDK5 | |
| SCHEMBL6067501 | 0.80 | — | — | |
| SCHEMBL7547350 | 0.80 | — | — | |
| SCHEMBL7542934 | 0.73 | LMNA (0.30) | — | |
| SCHEMBL7545657 | 0.73 | — | — | |
| SCHEMBL8861732 | 0.70 | HTR2A (0.51) | HTR2AHRH1RETCDK8CDK5 | |
| SCHEMBL17023011 | 0.68 | HTR2A (0.37) | HTR2AHRH1 | |
| SCHEMBL8854185 | 0.66 | CYP3A4 (0.41) | HTR2AHRH1 | |
| SCHEMBL7207620 | 0.65 | HTR2A (0.40) | HTR2AHRH1RET | |
| SCHEMBL8854188 | 0.64 | HTR2A (0.38) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610872-B1 | Zirconim complex containing a dialkylaminoalkylcyclopenta-dienyl or indenyl group and a hydorcarbon cyclopentadienyl group | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2003-08-26 | — | — | US | disclosed |
| US-6140448-A | Process for preparing polysilane by catalytic dehydrogenative condensation of organosilane and metal complex catalyst therefor | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2000-10-31 | — | — | US | disclosed |