Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 2/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2054229 | 0.92 | TYMP (0.39) | PRMT6TYMPP2RY12GAPDHPRKAG1 | |
| SCHEMBL29449394 | 0.92 | TYMP (0.39) | PRMT6TYMPP2RY12GAPDHPRKAG1 | |
| SCHEMBL15786367 | 0.92 | TYMP (0.39) | PRMT6TYMPP2RY12GAPDHPRKAG1 | |
| SCHEMBL29674590 | 0.92 | TYMP (0.39) | PRMT6TYMPP2RY12GAPDHPRKAG1 | |
| SCHEMBL30448691 | 0.88 | PRMT6 (0.39) | PRMT6TYMPP2RY12GAPDHPRKAG1 | |
| SCHEMBL26347688 | 0.88 | PRMT6 (0.39) | PRMT6TYMPP2RY12GAPDHPRKAG1 | |
| SCHEMBL23881919 | 0.87 | PRMT6 (0.34) | PRMT6GAPDHPRKAG1PRKAA1PRKAB1 | |
| SCHEMBL24115324 | 0.87 | TYMP (0.39) | PRMT6TYMPP2RY12PRKAG1PRKAA1 | |
| SCHEMBL441412 | 0.87 | ADORA2A (0.35) | PRMT6P2RY12PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL17231772 | 0.86 | P2RY12 (0.37) | PRMT6P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203356-A1 | RNase L activator-antisense complexes | THE CLEVELAND CLINIC FOUNDATION (US) | 2003-10-30 | — | — | US | disclosed |
| US-6214805-B1 | GENES, GENE SIGNALS, GENOMES RNA STRANDS AND RESPIRATORY SYNCYTIAL VIRUS WITH PROMOTERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-04-10 | — | — | US | disclosed |
| EP-1007655-A1 | RNASE L ACTIVATORS AND ANTISENSE OLIGONUCLEOTIDES EFFECTIVE TO TREAT RSV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5998602-A | RNase L activators and antisense oligonucleotides effective to treat RSV infections | THE CLEVELAND CLINIC FOUINDATION AND GOVERNMENT (US) | 1999-12-07 | — | — | US | disclosed |