⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530555 | 0.86 | SMYD3 (0.38) | — | |
| SCHEMBL8242432 | 0.80 | — | — | |
| SCHEMBL11435229 | 0.76 | — | — | |
| SCHEMBL19983239 | 0.76 | RAB9A (0.31) | — | |
| SCHEMBL17311800 | 0.75 | EPHX2 (0.50) | — | |
| SCHEMBL14653231 | 0.75 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL12536864 | 0.72 | MAPT (0.40) | — | |
| SCHEMBL10694797 | 0.71 | SMYD3 (0.32) | — | |
| SCHEMBL10529046 | 0.70 | KDM1A (0.36) | — | |
| SCHEMBL21974411 | 0.69 | CHRNB4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865443-B1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | DSM NV (NL) | 2003-03-19 | — | — | EP | claimed |
| US-6503727-B1 | The invention relates to a process for the preparation of an antibiotic, in particular cefalexin, ampicillin, amoxicillin, cefaclor, cefradin, cefadroxil, cefotaxim and the like, wherein a beta-lactam core is acylated, the antibiotic is | GIST-BROCADES, B.V. (NL) | 2003-01-07 | — | — | US | claimed |
| EP-0865443-A1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | GIST-BROCADES B.V. (NL) | 1998-09-23 | — | — | EP | claimed |
| WO-1997022610-A1 | PROCESS FOR THE PREPARATION OF AN ANTIBIOTIC | GIST-BROCADES B.V. (NL) | 1997-06-26 | — | — | WO | claimed |
| EP-0271023-A2 | Use of dihydrophenylamino-acid derivatives and medicines containing them for immunomodulation and cytostasis | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1988-06-15 | — | — | EP | claimed |
| JP-1153665-A | — | — | None | — | — | JP | disclosed |
| EP-2723882-A1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | DSM Sinochem Pharmaceuticals Netherlands B.V. (NL) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175585-A1 | PROCESS FOR PREPARING 3'-THIOSUBSTITUTED CEPHALOSPORINS EMPLOYING A PENICILLIN G ACYLASE | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2012-12-27 | — | — | WO | disclosed |
| JP-H01153665-A | USE OF DIHYDROPHENYLAMINO ACID DERIVATIVE FOR IMMUNOMODULATION AND CYTOSTASIS AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | GOEDECKE AG | 1989-06-15 | — | — | JP | disclosed |
| EP-0271023-A2 | Use of dihydrophenylamino-acid derivatives and medicines containing them for immunomodulation and cytostasis | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1988-06-15 | — | — | EP | disclosed |