Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216971 | 0.93 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL7206044 | 0.90 | FAAH (0.67) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL31597015 | 0.89 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| Hydrochloric Acid SCHEMBL7859272 | 0.89 | FAAH (0.66) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL16212683 | 0.88 | FAAH (0.64) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL9411411 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL7280086 | 0.86 | FAAH (0.62) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL7107231 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL30712276 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 | |
| SCHEMBL7281136 | 0.86 | HTT (0.65) | SMN1; SMN2NPC1RAB9AFAAHCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030831-A4 | PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES | AVENTIS PHARM PROD INC (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6180759-B1 | PREPARING AZACYCLOALKANOYLPSEUDOTETRAPEPTIDES COMPRISING COUPLING A DIPEPTIDE WITH A PSEUDODIPEPTIDE; FOR EXAMPLE, N-(N-ETHYL-N-(1-OXO-4-(4-PIPERIDINYL)BUTYL)GLYCYL)-(L)-ALPHA-ASPARTYL-3 -CYCLOHEXYL-(L)-ALANINEAMIDE; USE AS ANTICOAGULANTS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-01-30 | — | — | US | disclosed |
| EP-1030831-A1 | PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES | Aventis Pharmaceuticals Products Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999019294-A1 | PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES | AVENTIS PHARMACEUTICALS PRODUCTS INC. LEGAL/PATENTS (US) | 1999-04-22 | — | — | WO | disclosed |