Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | MC4R | P32245 | 14/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767273 | 0.86 | MC4R (0.53) | KCNH2MC4RPKM | |
| SCHEMBL5766154 | 0.85 | KCNH2 (0.53) | KCNH2MC4RPKM | |
| SCHEMBL7206492 | 0.84 | KCNH2 (0.58) | KCNH2MC4R | |
| SCHEMBL5766784 | 0.83 | KCNH2 (0.52) | KCNH2MC4R | |
| SCHEMBL5763829 | 0.81 | KCNH2 (0.50) | KCNH2MC4RPKM | |
| SCHEMBL5768686 | 0.81 | KCNH2 (0.50) | KCNH2MC4R | |
| SCHEMBL4067065 | 0.78 | KCNH2 (0.56) | KCNH2MC4R | |
| SCHEMBL5767776 | 0.77 | KCNH2 (0.52) | KCNH2MC4R | |
| SCHEMBL5767311 | 0.76 | KCNH2 (0.50) | KCNH2MC4R | |
| SCHEMBL5766403 | 0.76 | KCNH2 (0.50) | KCNH2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363890-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2003-11-26 | — | — | EP | claimed |
| WO-2002062766-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | claimed |
| EP-1363890-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002062766-A2 | MELANOCORTIN-4 RECEPTOR BINDING COMPOUNDS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-08-15 | — | — | WO | disclosed |