Styrene

Styrene

SCHEMBL720652

C=C(C)C(=O)OC.C=C(C=CC(=O)O)C(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.42
KDM4E B2RXH2 2/20 0.41
TSHR P16473 4/20 0.40
HCAR2 Q8TDS4 3/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 1/20 0.40
POLB P06746 2/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP3A4 P08684 1/20 0.34
MAPK1 P28482 1/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL250640 0.92 HCAR2 (0.47) TDP1KDM4ETSHRHCAR2SMN1; SMN2
Styrene SCHEMBL11501866 0.92 TSHR (0.40) TDP1KDM4ETSHRHCAR2SMN1; SMN2
Styrene SCHEMBL15158014 0.91 TSHR (0.43) TDP1KDM4ETSHRHCAR2SMN1; SMN2
Styrene SCHEMBL10623518 0.90 TSHR (0.50) TDP1KDM4ETSHRHCAR2SMN1; SMN2
Styrene SCHEMBL10623522 0.90 TSHR (0.50) TDP1KDM4ETSHRHCAR2SMN1; SMN2
Styrene SCHEMBL4210153 0.90 TSHR (0.50) TDP1KDM4ETSHRSMN1; SMN2L3MBTL1
Styrene SCHEMBL6375723 0.89 MEN1 (0.45) TDP1KDM4ESMN1; SMN2L3MBTL1ALDH1A1
Styrene SCHEMBL8586039 0.89 TSHR (0.47) TDP1KDM4ETSHRSMN1; SMN2L3MBTL1
Styrene SCHEMBL472828 0.88 TDP1 (0.47) TDP1KDM4ETSHRHCAR2ALDH1A1
Styrene SCHEMBL8094495 0.88 HCAR2 (0.49) KDM4ETSHRHCAR2SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4321169-A Water based alkyd resin coating composition containing a polyisocyanate crosslinking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-23 US claimed
US-4288351-A ALKYLATED MELAMINE-FORMALDEHYDE RESIN, ACRYLIC DISPERSANT, ORGANOMETALLIC DRIER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-08 US claimed
WO-2023146911-A1 NON-FLUORINATED SURFACTANTS FOR FLOOR CARE COATINGS BASF SE (DE) 2023-08-03 WO disclosed
US-20230080941-A1 COMPOSITIONS AND METHOD FOR FLOOR CLEANING OR RESTORATION ECOLAB USA INC. 2023-03-16 US disclosed
EP-3099749-B1 AQUEOUS SURFACE COATING COMPOSITION AND MODIFIED PARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2021-02-24 EP disclosed
US-20210024854-A1 COMPOSITIONS AND METHOD FOR FLOOR CLEANING OR RESTORATION ECOLAB USA INC. 2021-01-28 US disclosed
US-10774292-B2 Compositions and method for floor cleaning or restoration ECOLAB USA INC. (US) 2020-09-15 US disclosed
CN-105940062-B Aqueous surface coating composition and modified particles 3M创新有限公司 2020-04-10 CN disclosed
CN-110573601-A Compositions and methods for floor cleaning or rehabilitation 埃科莱布美国股份有限公司 2019-12-13 CN disclosed
US-10465079-B2 Aqueous surface coating composition and modified particles comprising hydrophobic and hydrophilic moieties 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-05 US disclosed
US-20180327694-A1 COMPOSITIONS AND METHOD FOR FLOOR CLEANING OR RESTORATION ECOLAB USA INC. 2018-11-15 US disclosed
WO-1996000751-A1 POWDER COATING COMPOSITIONS S. C. JOHNSON & SON, INC. (US) 1996-01-11 WO disclosed
EP-0246928-B1 FLOOR POLISHING COMPOSITION S.C. JOHNSON & SON, INC. (US) 1992-09-30 EP disclosed
US-4960463-A UPGRADING SURFACE PHYSICAL PROPERTIES BY ADDING ALKOXYLATED AMINE SURFACTANT S. C. JOHNSON & SON, INC. (US) 1990-10-02 US disclosed
US-4923514-A POLYMER AND ALKOXYLATED AMINE SURFACTANT; LEVELING, GLOSS S. C. JOHNSON & SON, INC. (US) 1990-05-08 US disclosed
EP-0246928-A2 Floor polishing composition S.C. JOHNSON & SON, INC. (US) 1987-11-25 EP disclosed
EP-0068902-A1 Water-developable lithographic printing plate material KONICA CORPORATION (JP) 1983-01-05 EP disclosed
US-4321169-A Water based alkyd resin coating composition containing a polyisocyanate crosslinking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-23 US disclosed
US-4288351-A ALKYLATED MELAMINE-FORMALDEHYDE RESIN, ACRYLIC DISPERSANT, ORGANOMETALLIC DRIER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-09-08 US disclosed
US-3980602-A STYRENE ANDOR ALKYL METHACRYLATE, ALKYL ACRYLATE, ACRYLIC OR METHACRYLIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-14 US disclosed