Styrene

Styrene

SCHEMBL8094495

C=C(C=CC(=O)O)C(=O)OCCCCCC.C=Cc1ccccc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.49
ALDH1A1 P00352 3/20 0.48
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
KDM4E B2RXH2 3/20 0.48
MAPT P10636 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 4/20 0.45
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
POLB P06746 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PPARG P37231 3/20 0.40
EGFR P00533 1/20 0.40
APP P05067 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL18297752 1.00 HCAR2 (0.49) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL250640 0.95 HCAR2 (0.47) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL8469665 0.92 KDM4E (0.42) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL8516972 0.90 HCAR2 (0.44) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL9718413 0.89 HCAR2 (0.48) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL11122929 0.89 KDM4E (0.44) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL15158014 0.88 TSHR (0.43) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL720652 0.88 TDP1 (0.42) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL2417399 0.87 ALDH1A1 (0.37) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E
Styrene SCHEMBL8508729 0.86 HCAR2 (0.68) HCAR2ALDH1A1LMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886065-A WATERFASTNESS, NON-FLOCCULATING HEWLETT-PACKARD COMPANY (US) 1999-03-23 US claimed
US-6034153-A STABLE COLORANT HEWLETT-PACKARD COMPANY (US) 2000-03-07 US disclosed
US-5886065-A WATERFASTNESS, NON-FLOCCULATING HEWLETT-PACKARD COMPANY (US) 1999-03-23 US disclosed