Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089450 | 1.00 | CASR (0.54) | CASRPOLBMAPK1KMT2AKDM4E | |
| SCHEMBL14022027 | 0.86 | POLB (0.50) | CASRPOLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL14021981 | 0.86 | POLB (0.50) | CASRPOLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL3734404 | 0.82 | CASR (0.54) | CASRKMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3734407 | 0.82 | CASR (0.54) | CASRKMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL9088241 | 0.81 | MEN1 (0.50) | CASRKMT2AKDM4EALDH1A1 | |
| SCHEMBL7181177 | 0.81 | MEN1 (0.50) | CASRKMT2AKDM4EALDH1A1 | |
| SCHEMBL7188815 | 0.79 | POLB (0.55) | CASRPOLBCYP2D6 | |
| SCHEMBL9086674 | 0.79 | POLB (0.55) | CASRPOLBCYP2D6 | |
| SCHEMBL3736990 | 0.79 | CASR (0.51) | CASRKMT2AALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907631-B1 | INORGANIC ION RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2003-06-18 | — | — | EP | disclosed |