Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASR | P41180 | 3/20 | 0.47 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022027 | 1.00 | POLB (0.50) | POLBCASRKRASSOS1PTGER4 | |
| SCHEMBL7206660 | 0.86 | CASR (0.54) | POLBCASRKMT2AKDM4EALDH1A1 | |
| SCHEMBL9089450 | 0.86 | CASR (0.54) | POLBCASRKMT2AKDM4EALDH1A1 | |
| SCHEMBL14022028 | 0.79 | POLB (0.50) | POLBKMT2AALDH1A1HTT | |
| SCHEMBL14022026 | 0.76 | GABRA1 (0.44) | POLBKMT2AKDM4EALDH1A1HTT | |
| SCHEMBL3734404 | 0.75 | CASR (0.54) | CASRKMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL3734407 | 0.75 | CASR (0.54) | CASRKMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL7181177 | 0.74 | MEN1 (0.50) | CASRKRASSOS1KMT2AKDM4E | |
| SCHEMBL9088241 | 0.74 | MEN1 (0.50) | CASRKRASSOS1KMT2AKDM4E | |
| SCHEMBL9086674 | 0.72 | POLB (0.55) | POLBCASRMLNRABCB11ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135386-A1 | CHIRAL LIGANDS OF THE N-HETEROCYCLIC CARBENE TYPE FOR ASYMMETRICAL CATALYSIS | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2008-11-13 | — | — | WO | disclosed |