Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205531 | 0.85 | TSHR (0.43) | ALDH1A1KDM4EHSD17B10HPGDGLA | |
| SCHEMBL4790589 | 0.71 | POLB (0.45) | ALDH1A1MAPTHPGDRAB9ACYP11B1 | |
| SCHEMBL7336875 | 0.69 | CYP11B1 (0.42) | ALDH1A1KDM4EHSD17B10MAPTCYP11B1 | |
| SCHEMBL14944610 | 0.69 | AR (0.40) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL2567869 | 0.68 | ADORA2A (0.48) | ALDH1A1KDM4EMAPTHPGDGLA | |
| SCHEMBL4058117 | 0.68 | CDK1 (0.38) | ALDH1A1MAPTTP53NPSR1 | |
| SCHEMBL5732110 | 0.67 | ADORA2A (0.53) | ALDH1A1LMNATSHRCYP3A4CYP2C9 | |
| SCHEMBL7209444 | 0.67 | TLR7 (0.38) | ALDH1A1KDM4EMAPTHPGDGLA | |
| SCHEMBL18207487 | 0.67 | KMT2A (0.52) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL16833355 | 0.66 | SLC2A1 (0.67) | ALDH1A1KDM4EHSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |