Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206699 | 0.85 | ALDH1A1 (0.40) | TSHRKMT2AMEN1LMNAHTT | |
| SCHEMBL2567869 | 0.82 | ADORA2A (0.48) | TSHRKMT2AMEN1EGLN1L3MBTL1 | |
| SCHEMBL14839377 | 0.74 | PNP (0.42) | TSHRKMT2AMEN1HTTALDH1A1 | |
| SCHEMBL3130833 | 0.69 | ADORA2A (0.47) | TSHRKMT2AMEN1LMNAHPGD | |
| SCHEMBL1076537 | 0.69 | TSHR (0.60) | TSHRKMT2AMEN1LMNAHTT | |
| SCHEMBL10888984 | 0.69 | HPGD (0.55) | TSHRHTTHPGDALDH1A1 | |
| SCHEMBL15432549 | 0.69 | CYP11B1 (0.40) | KMT2AMEN1LMNAHTTHPGD | |
| SCHEMBL7212493 | 0.69 | ADORA2A (0.47) | TLR7 | |
| SCHEMBL2060235 | 0.68 | TLR7 (0.42) | TLR7 | |
| SCHEMBL14944610 | 0.68 | AR (0.40) | TSHRKMT2ALMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |
| JP-2000159767-A | NEW PRODUCTION PROCESS FOR 8-HYDROXYADENINE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 2000-06-13 | — | — | JP | disclosed |