Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5124000 | 0.85 | CYP2C19 (0.47) | CHRM2CHRM1CHRM3CYP2C19SMN1; SMN2 | |
| SCHEMBL5116776 | 0.82 | BCHE (0.51) | CHRM2CHRM1CHRM3CYP2C19SMN1; SMN2 | |
| SCHEMBL5110138 | 0.82 | BCHE (0.51) | CHRM2CHRM1CHRM3CYP2C19SMN1; SMN2 | |
| SCHEMBL5116779 | 0.82 | BCHE (0.51) | CHRM2CHRM1CHRM3CYP2C19SMN1; SMN2 | |
| SCHEMBL5113701 | 0.82 | BCHE (0.51) | CHRM2CHRM1CHRM3CYP2C19SMN1; SMN2 | |
| SCHEMBL5118683 | 0.81 | BCHE (0.52) | CHRM2CHRM1CHRM3CYP2C19SMN1; SMN2 | |
| SCHEMBL915402 | 0.77 | KMT2A (0.65) | DPP7KMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL5123997 | 0.76 | CYP2C19 (0.51) | CHRM2CHRM1CHRM3CYP2C19SMN1; SMN2 | |
| SCHEMBL555464 | 0.75 | KMT2A (0.64) | CHRM2CHRM1CHRM3DPP7KMT2A | |
| SCHEMBL4200905 | 0.74 | CTSS (0.53) | CYP2C19SMN1; SMN2KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605608-B1 | Such as n-(1-benzylpiperidin-4-yl)-3-cyclohexylmethylthio-2-((4R)-3-t -butoxycarbonylthiazolidin-4-ylcarbonylamino)propan-a mide; n-type calcium channel inhibitors | ONO PHARMACEUTICAL CO., LTD (JP) | 2003-08-12 | — | — | US | disclosed |