Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.76 |
| ▸ | CAPN1 | P07384 | 14/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6735420 | 1.00 | CTSK (0.76) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL913603 | 1.00 | CTSK (0.76) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL913547 | 0.99 | CTSK (0.74) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL2730672 | 0.99 | CTSK (0.74) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL6742223 | 0.88 | CTSK (0.60) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL6742229 | 0.88 | CTSK (0.60) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL6738598 | 0.87 | CTSK (0.58) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL6738594 | 0.87 | CTSK (0.58) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| Potassium Ion SCHEMBL913496 | 0.86 | CTSK (0.95) | CTSKCAPN1CTSBCAPN9MAPK1 | |
| SCHEMBL913738 | 0.86 | CTSK (1.00) | CTSKCAPN1CTSBCAPN9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022276-B1 | EPOXYSUCCINAMIDE DERIVATIVES | NIPPON CHEMIPHAR CO (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6387908-B1 | BONE DISORDERS; ANTIARTHRITIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1022276-A1 | EPOXYSUCCINAMIDE DERIVATIVES | NIPPON CHEMIPHAR CO., LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |