Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211954 | 1.00 | PLA2G2A (0.56) | PLA2G2A | |
| SCHEMBL7965541 | 0.91 | PLA2G2A (0.52) | PLA2G2A | |
| SCHEMBL7965543 | 0.91 | PLA2G2A (0.52) | PLA2G2A | |
| SCHEMBL7968638 | 0.91 | PLA2G2A (0.60) | PLA2G2A | |
| SCHEMBL7208320 | 0.91 | PLA2G2A (0.60) | PLA2G2A | |
| SCHEMBL7206879 | 0.87 | PLA2G2A (0.44) | PLA2G2A | |
| SCHEMBL9268578 | 0.86 | PLA2G2A (0.69) | PLA2G2A | |
| SCHEMBL7207538 | 0.84 | PLA2G2A (0.61) | PLA2G2A | |
| SCHEMBL7968970 | 0.81 | PLA2G2A (0.56) | PLA2G2A | |
| SCHEMBL7968973 | 0.81 | PLA2G2A (0.56) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | claimed |
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | claimed |
| EP-0923546-A1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | Merckle GmbH (DE) | 1999-06-23 | — | — | EP | claimed |
| WO-1998005637-A1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A¿2? | MERCKLE GMBH (DE) | 1998-02-12 | — | — | WO | claimed |
| EP-0923546-B1 | ACYLPYRROLDICARBOXYLIC ACIDS AND ACYLINDOLDICARBOXYLIC ACIDS AND THEIR DERIVATIVES AND INHIBITORS OF THE CYTOSOLIC PHOSPHOLIPASE A2 | MERCKLE GMBH (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | disclosed |