Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190366 | 0.84 | TSHR (0.62) | PYCR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL347820 | 0.82 | TSHR (0.61) | PYCR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL8713184 | 0.81 | TSHR (0.69) | PYCR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL7934234 | 0.79 | TSHR (0.57) | PYCR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL1978577 | 0.79 | PYCR1 (0.55) | PYCR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL10918542 | 0.79 | TSHR (0.71) | PYCR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL94845 | 0.77 | TSHR (0.69) | PYCR1TSHRLMNACYP1A2CYP2D6 | |
| SCHEMBL12415808 | 0.77 | PYCR1 (0.57) | PYCR1TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4521415 | 0.77 | PYCR1 (0.57) | PYCR1TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9350384 | 0.76 | MEN1 (0.41) | PYCR1TSHRLMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | claimed |