Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.30 |
| ▸ | CDK9 | P50750 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827034 | 0.85 | MAOA (0.33) | BTKTRPV1 | |
| SCHEMBL7079336 | 0.76 | MAOA (0.32) | BTK | |
| SCHEMBL7085167 | 0.75 | F10 (0.36) | BTKCCNT1CDK9 | |
| SCHEMBL7085165 | 0.75 | F10 (0.36) | BTKCCNT1CDK9 | |
| Posizolid SCHEMBL3039615 | 0.75 | MAOA (0.34) | BTKTRPV1 | |
| Posizolid SCHEMBL374786 | 0.75 | MAOA (0.34) | BTKTRPV1 | |
| SCHEMBL7081128 | 0.75 | MAOA (0.34) | — | |
| Posizolid SCHEMBL7079325 | 0.75 | MAOA (0.34) | BTKTRPV1 | |
| SCHEMBL7081127 | 0.75 | MAOA (0.34) | — | |
| Posizolid SCHEMBL14286008 | 0.75 | MAOA (0.34) | BTKTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003515539-A | — | — | 2003-05-07 | — | — | JP | claimed |
| EP-1237895-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | AstraZeneca AB (SE) | 2002-09-11 | — | — | EP | claimed |
| WO-2001040236-A2 | PHOSPHORYLATION OF TERMINAL PRIMARY ALCOHOL GROUPS | ASTRAZENECA AB (SE) | 2001-06-07 | — | — | WO | claimed |