SCHEMBL7207290

SCHEMBL7207290

CCC(C=O)(CC)CC#Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
THPO P40225 1/20 0.41
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
HTR2A P28223 1/20 0.40
APP P05067 1/20 0.37
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
SIGMAR1 Q99720 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
PYCR1 P32322 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2156550 0.79 CYP1A2 (0.44) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL32234906 0.71 CYP1A2 (0.52) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL97269 0.69 CYP1A2 (0.54) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL9784153 0.68 NPSR1 (0.63) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2092478 0.68 NPSR1 (0.63) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL16058422 0.68 GAA (0.53) NPSR1KMT2ALMNAMEN1ALDH1A1
SCHEMBL3660905 0.67 CYP1A2 (0.52) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL19359252 0.67 CYP3A4 (0.47) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL28315429 0.67 LMNA (0.40) CYP1A2CYP3A4CYP2C9CYP2C19KMT2A
Hydrochloric Acid SCHEMBL7362587 0.66 NPSR1 (0.61) NPSR1CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6613945-B1 Resolution method for a racemic mixture of aldehydes RHODIA CHIMIE (FR) 2003-09-02 US disclosed