Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 3/20 | 0.56 |
| ▸ | TDO2 | P48775 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24017114 | 0.87 | PNMT (0.59) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL15137235 | 0.87 | PNMT (0.59) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL29897739 | 0.87 | PNMT (0.59) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL9679731 | 0.87 | PNMT (0.59) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL40102 | 0.83 | HTR2A (0.58) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL334964 | 0.83 | HTR2A (0.58) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL3446710 | 0.83 | PNMT (0.56) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL1728826 | 0.83 | HTR2A (0.58) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL1819656 | 0.83 | PNMT (0.56) | PNMTIDO1TDO2TSHRMAPK1 | |
| SCHEMBL29504910 | 0.83 | HTR2A (0.58) | PNMTIDO1TDO2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |