SCHEMBL7207431

SCHEMBL7207431

CC(C)(C)OC(=O)[C@](N)(CC1CCCCC1)C(=O)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.40
ALDH1A1 P00352 2/20 0.40
FKBP1A P62942 1/20 0.39
EPHX1 P07099 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CTSB P07858 1/20 0.38
CTSS P25774 1/20 0.38
CTSK P43235 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.38
SYK P43405 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27538081 0.87 ALDH1A1 (0.43) CTSLALDH1A1EPHX1NPC1RAB9A
SCHEMBL6016191 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MEN1KMT2ASYK
SCHEMBL27697836 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MEN1KMT2ASYK
SCHEMBL27703135 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4
SCHEMBL8884912 0.80 SMN1; SMN2 (0.50) ALDH1A1NPC1RAB9ASMN1; SMN2KMT2A
SCHEMBL1731417 0.79 ALDH1A1 (0.45) CTSLALDH1A1SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL7444531 0.79 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2MEN1KMT2ASYK
SCHEMBL22962924 0.79 ALDH1A1 (0.48) ALDH1A1FKBP1AEPHX1NPC1RAB9A
SCHEMBL1731415 0.79 ALDH1A1 (0.45) CTSLALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL11169957 0.79 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1030831-A4 PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES AVENTIS PHARM PROD INC (US) 2003-01-02 EP disclosed
EP-1030831-A1 PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES Aventis Pharmaceuticals Products Inc. (US) 2000-08-30 EP disclosed
WO-1999019294-A1 PROCESS FOR THE PREPARATION OF AZACYCLOALKYLALKANOYL PSEUDOTETRAPEPTIDES AVENTIS PHARMACEUTICALS PRODUCTS INC. LEGAL/PATENTS (US) 1999-04-22 WO disclosed