Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204110 | 0.78 | — | — | |
| SCHEMBL11101825 | 0.76 | — | — | |
| SCHEMBL16659207 | 0.76 | LMNA (0.39) | LMNAALDH1A1PKMMIFCASP6 | |
| SCHEMBL7211837 | 0.75 | KDM4E (0.35) | LMNAALDH1A1PKMSMN1; SMN2MAPT | |
| SCHEMBL7212655 | 0.71 | SMN1; SMN2 (0.49) | LMNAALDH1A1PKMCASP6SMN1; SMN2 | |
| SCHEMBL15101226 | 0.69 | — | — | |
| SCHEMBL10662134 | 0.69 | — | — | |
| SCHEMBL16328593 | 0.69 | — | — | |
| SCHEMBL14900659 | 0.67 | LMNA (0.33) | LMNAALDH1A1PKMMIFCASP6 | |
| SCHEMBL5407808 | 0.67 | LMNA (0.33) | LMNAALDH1A1PKMMIFCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023272-B1 | PROCESS FOR PREPARING ALKOXYTRIAZOLINONES | LONZA AG (CH) | 2003-07-16 | — | — | EP | claimed |
| US-6376699-B1 | FROM HYDRAZINECARBOXYLIC ESTER; CYCLIZATION | LONZA AG (CH) | 2002-04-23 | — | — | US | claimed |
| US-6376699-B1 | FROM HYDRAZINECARBOXYLIC ESTER; CYCLIZATION | LONZA AG (CH) | 2002-04-23 | — | — | US | disclosed |
| US-6248900-B1 | REACTING AN IMINOCARBONIC DIESTER WITH A CARBAZINIC ESTER IN PRESENCE OF MINERAL ACID TO GIVE A HYDRAZINECARBOXYLIC ESTER; CYCLIZING PRODUCT WITH PRIMARY AMINE; WATER AND/OR POLAR ORGANIC SOLVENT | LONZA GROUP (CH) | 2001-06-19 | — | — | US | disclosed |