SCHEMBL7207562

SCHEMBL7207562

CCCCCCCC#Cc1cccc(F)n1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.50
GRM5 P41594 3/20 0.44
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
MMP2 P08253 1/20 0.36
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7678409 0.78 KCNH2 (0.50) KCNH2GRM5FFAR1FFAR4MMP2
SCHEMBL7682931 0.78 KCNH2 (0.50) KCNH2GRM5FFAR1FFAR4MMP2
SCHEMBL7678625 0.78 KCNH2 (0.50) KCNH2GRM5FFAR1FFAR4MMP2
SCHEMBL28954282 0.75 GRM5 (0.45) KCNH2GRM5FFAR1FFAR4MMP2
SCHEMBL22342613 0.75 KCNH2 (0.43) KCNH2GRM5FFAR1FFAR4MMP2
SCHEMBL22342612 0.75 KCNH2 (0.43) KCNH2GRM5FFAR1FFAR4MMP2
SCHEMBL9234412 0.74 GRM5 (0.47) KCNH2GRM5
SCHEMBL20917342 0.74 KCNH2 (0.39) KCNH2GRM5FFAR1FFAR4MMP2
SCHEMBL22031490 0.73 ALDH1A1 (0.37) GRM5
SCHEMBL8639129 0.72 KCNH2 (0.46) KCNH2GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6605323-B1 Monostable ferroelectric active matrix display AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 2003-08-12 US disclosed