Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21740318 | 0.98 | SOS1 (0.42) | SOS1SOS2 | |
| SCHEMBL24801938 | 0.91 | SOS1 (0.48) | SOS1SOS2 | |
| Trifluoroacetic Acid SCHEMBL31579834 | 0.87 | SOS1 (0.35) | SOS1SOS2 | |
| SCHEMBL18828765 | 0.81 | SOS1 (0.43) | SOS1SOS2 | |
| SCHEMBL18706072 | 0.80 | SOS1 (0.39) | SOS1SOS2 | |
| SCHEMBL31276193 | 0.78 | SOS1 (0.38) | SOS1SOS2 | |
| SCHEMBL617658 | 0.78 | SOS1 (0.39) | SOS1SOS2 | |
| SCHEMBL13383209 | 0.76 | CYP3A4 (0.32) | SOS1SOS2 | |
| SCHEMBL799357 | 0.74 | SOS1 (0.35) | SOS1SOS2 | |
| SCHEMBL10263734 | 0.74 | SOS1 (0.35) | SOS1SOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1108738-B1 | Immunostimulating carrier for vaccines | PETROVAX INC (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-0789586-B1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF HELMINTH INFECTIONS | PETROVAX INC (US) | 2001-07-04 | — | — | EP | disclosed |
| EP-1108738-A2 | Immunostimulating carrier for vaccines | Petrovax, Inc. (US) | 2001-06-20 | — | — | EP | disclosed |
| EP-0789586-A4 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF HELMINTH INFECTIONS | PETROVAX INC (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5811100-A | HYALURONIDASE COVALENTLY COUPLED TO IMMUNOSTIMULATING CARRIER | PETROVAX, INC. (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0789586-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF HELMINTH INFECTIONS | Petrovax, Inc. (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1995007100-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF HELMINTH INFECTIONS | PETROVAX L.L.C. (US) | 1995-03-16 | — | — | WO | disclosed |