SCHEMBL21740318

SCHEMBL21740318

CC(=O)N1CCNCC12CC2

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.42
SOS2 Q07890 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7207572 0.98 SOS1 (0.41) SOS1SOS2
SCHEMBL24801938 0.92 SOS1 (0.48) SOS1SOS2
Trifluoroacetic Acid SCHEMBL31579834 0.88 SOS1 (0.35) SOS1SOS2
SCHEMBL18828765 0.83 SOS1 (0.43) SOS1SOS2
SCHEMBL18706072 0.82 SOS1 (0.39) SOS1SOS2
SCHEMBL31276193 0.80 SOS1 (0.38) SOS1SOS2
SCHEMBL617658 0.79 SOS1 (0.39) SOS1SOS2
SCHEMBL13383209 0.78 CYP3A4 (0.32) SOS1SOS2
SCHEMBL799357 0.76 SOS1 (0.35) SOS1SOS2
SCHEMBL10263734 0.76 SOS1 (0.35) SOS1SOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331035-B2 Bicyclic compound and use thereof SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-06-17 US disclosed
EP-4050006-B1 BICYCLIC COMPOUND AND USE THEREOF SK BIOPHARMACEUTICALS CO LTD (KR) 2025-01-01 EP disclosed
WO-2024243485-A1 CDK2 INHIBITORS AND USES THEREOF ODYSSEY THERAPEUTICS, INC. (US) 2024-11-28 WO disclosed
US-20230023140-A1 BICYCLIC COMPOUND AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2023-01-26 US disclosed
EP-4050006-A1 BICYCLIC COMPOUND AND USE THEREOF SK Biopharmaceuticals Co., Ltd. (KR) 2022-08-31 EP disclosed
CN-114945562-A Bicyclic compounds and uses thereof 爱思开生物制药株式会社 2022-08-26 CN disclosed
WO-2021080359-A1 BICYCLIC COMPOUND AND USE THEREOF 에스케이바이오팜 주식회사 2021-04-29 WO disclosed
WO-2020037079-A1 SUBSTITUTED INDOLES AND METHODS OF USE THEREOF Epizyme, Inc. (US) 2020-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023140-A1 BICYCLIC COMPOUND AND USE THEREOF PRMT5, PRMT6, PRMT1 SOS1 4536/4885SOS2 4527/4885
US-12331035-B2 Bicyclic compound and use thereof PRMT5, PRMT6, PRMT1 SOS1 4536/4885SOS2 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.