Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.66 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338591 | 0.98 | CHRNB2 (0.68) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL171896 | 0.98 | CHRNB2 (0.68) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL422229 | 0.89 | CYP2C9 (0.70) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL23596366 | 0.87 | CHRNB2 (0.60) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL20730105 | 0.87 | CHRNB2 (0.64) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL19055583 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL9367178 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL4888697 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL30542607 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL3229561 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4CYP3A4CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| CN-1224426-A | 3-descladinose-2, 3-anhydroerythromycin derivatives | ABBOTT LAB (US) | 1999-07-28 | — | — | CN | disclosed |
| EP-0922050-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997042205-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | disclosed |