Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211829 | 1.00 | HTT (0.46) | HTTHSD17B3MAPTMEN1ALDH1A1 | |
| SCHEMBL7211834 | 0.73 | HSD17B3 (0.50) | HTTHSD17B3MAPTMEN1ALDH1A1 | |
| SCHEMBL7207694 | 0.73 | HSD17B3 (0.50) | HTTHSD17B3MAPTMEN1ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL27597692 | 0.70 | SOAT1 (0.49) | HTTMAPTMEN1ALDH1A1KMT2A | |
| Hydrogen Peroxide SCHEMBL29233362 | 0.70 | SOAT1 (0.49) | HTTMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28216154 | 0.69 | HTT (0.49) | HTTHSD17B3MAPTMEN1ALDH1A1 | |
| SCHEMBL1944994 | 0.67 | HTT (0.53) | HTTHSD17B3MAPTMEN1ALDH1A1 | |
| SCHEMBL10643638 | 0.67 | HTT (0.47) | HTTHSD17B3MAPTMEN1ALDH1A1 | |
| SCHEMBL15676413 | 0.66 | MAPT (0.51) | HTTHSD17B3MAPTMEN1ALDH1A1 | |
| SCHEMBL10350952 | 0.66 | HTT (0.61) | HTTHSD17B3MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |