Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211834 | 1.00 | HSD17B3 (0.50) | HSD17B3FFAR1PLA2G2APLA2G5CA2 | |
| SCHEMBL14900694 | 0.74 | HSD17B3 (0.68) | HSD17B3FFAR1PLA2G2APLA2G5CA2 | |
| SCHEMBL5570402 | 0.74 | HSD17B3 (0.58) | HSD17B3FFAR1PLA2G2APLA2G5CA2 | |
| SCHEMBL7211829 | 0.73 | HTT (0.46) | HSD17B3FFAR1PLA2G2APLA2G5THRA | |
| SCHEMBL7207692 | 0.73 | HTT (0.46) | HSD17B3FFAR1PLA2G2APLA2G5THRA | |
| SCHEMBL13085847 | 0.73 | HSD17B3 (0.85) | HSD17B3THRATHRBMEN1ALDH1A1 | |
| SCHEMBL13085794 | 0.73 | HSD17B3 (0.85) | HSD17B3THRATHRBMEN1ALDH1A1 | |
| SCHEMBL23043728 | 0.73 | PLA2G2A (0.64) | HSD17B3FFAR1PLA2G2APLA2G5CA2 | |
| SCHEMBL29178478 | 0.73 | PLA2G2A (0.64) | HSD17B3FFAR1PLA2G2APLA2G5CA2 | |
| SCHEMBL10351383 | 0.73 | PLA2G2A (0.64) | HSD17B3FFAR1PLA2G2APLA2G5CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |