SCHEMBL720782

SCHEMBL720782

O=C(OF)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.64
F2 P00734 1/20 0.64
TSHR P16473 6/20 0.58
TDP1 Q9NUW8 4/20 0.52
TP53 P04637 1/20 0.52
ALDH1A1 P00352 4/20 0.50
KMT2A Q03164 3/20 0.50
MAPT P10636 3/20 0.50
CES1 P23141 3/20 0.50
CES2 O00748 2/20 0.50
POLB P06746 2/20 0.50
MAPK1 P28482 1/20 0.50
HIF1A Q16665 1/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28840271 0.97 LMNA (0.61) LMNAF2TSHRTDP1TP53
SCHEMBL28762534 0.97 LMNA (0.61) LMNAF2TSHRTDP1TP53
Water SCHEMBL28059023 0.97 LMNA (0.61) LMNAF2TSHRTDP1TP53
Fluoromethane SCHEMBL28310899 0.95 TSHR (0.60) LMNAF2TSHRTDP1TP53
SCHEMBL3794586 0.93 LMNA (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL27296187 0.86 PDCD1 (0.58) LMNAF2MAPTHIF1ASMN1; SMN2
SCHEMBL9627860 0.86 CA1 (0.44) LMNAF2TSHRTDP1TP53
SCHEMBL28853380 0.84 TSHR (0.48) LMNAF2TSHRTDP1TP53
SCHEMBL24036696 0.82 TSHR (0.60) TSHRTP53ALDH1A1MAPTCES1
SCHEMBL1029289 0.80 LMNA (0.73) LMNAF2TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121378786-B Rare earth metal-organic framework material, preparation method and application thereof 江西理工大学 2026-05-19 CN claimed
CN-118878854-A Preparation of metal organic framework material and application of metal organic framework material in flue gas desulfurization and dehumidification 南开大学 2024-11-01 CN claimed
CN-118834396-A Metal-organic framework material suitable for propylene-propane adsorption separation and preparation method thereof 南开大学 2024-10-25 CN claimed
CN-118146099-A Preparation method of 3-nitro-2-fluorobenzoic acid 张家港保税区三骏化工有限公司 2024-06-07 CN claimed
CN-117393860-B Quick-charging electrolyte, battery filling method and battery 天津力神电池股份有限公司 2024-02-27 CN claimed
CN-117393860-A Quick-charging electrolyte, battery filling method and battery 天津力神电池股份有限公司 2024-01-12 CN claimed
CN-114907571-B Preparation and application of Eu metal-organic framework material based on difunctional pyridine carboxylic acid porphyrin ligand 北京工业大学 2023-09-12 CN claimed
CN-114854033-B Preparation and application of Eu metal-organic framework material based on non-planar porphyrin ligand 北京工业大学 2023-09-01 CN claimed
CN-111187169-B Preparation process of fluorobenzene derivative and benzoic acid hypofluorite derivative 福建永晶科技股份有限公司 2023-05-09 CN claimed
CN-111348983-B Process for preparing fluorobenzene and benzoic acid hypofluoride 福建永晶科技股份有限公司 2023-03-07 CN claimed
EP-1114812-B1 PROCESSES FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS OTSUKA PHARMA CO LTD (JP) 2007-06-20 EP claimed
CN-1817881-A Production of stilsarin coarse products TIANYUAN PHARMACEUTICAL CO LTD (CN) 2006-08-16 CN claimed
CN-1671644-A Compounds that abrogate DNA-damage-induced cell cycle G2 checkpoint and/or augment the anti-cancer activity of DNA-damaging treatments CANBAS CO LTD (JP) 2005-09-21 CN claimed
US-6333431-B1 ALKYLATING TETRAFLUOROBENZOIC ACID OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2001-12-25 US claimed
CN-1068867-C Preparation of 2,3,4,5-tetrafluorobenzoic acid HUADONG SCIENCE & ENGINEERING (CN) 2001-07-25 CN claimed
EP-1114812-A1 PROCESSES FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2001-07-11 EP claimed
CN-1201779-A Preparation of 2,3,4,5-tetrafluorobenzoic acid HUADONG SCIENCE & ENGINEERING (CN) 1998-12-16 CN claimed
CN-1118344-A Processes for producing tetrafluorophthalic anhydride and fluorobenzoic acids ASAHI CO LTD (JP) 1996-03-13 CN claimed
CN-1014147-B Improved process for the preparation of tetrafluorobenzoic acids WARNER LAMBERT CO (US) 1991-10-02 CN claimed
CN-86106151-A The improved method for preparing tetrafluorobenzoic aid 1987-06-03 CN claimed