Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL30428100 | 0.92 | FFAR3 (0.54) | LMNAFFAR3LCKFYNALDH1A1 | |
| Acetone SCHEMBL8887669 | 0.88 | — | — | |
| Benzene SCHEMBL28286894 | 0.86 | LMNA (0.53) | LMNAFFAR3LCKFYNALDH1A1 | |
| Pyruvate SCHEMBL28154876 | 0.86 | AKR1C3 (0.39) | LMNAFFAR3LCKFYNALDH1A1 | |
| Acetic Acid SCHEMBL6905387 | 0.84 | FFAR3 (0.64) | LMNAFFAR3LCKFYNALDH1A1 | |
| Acetic Acid SCHEMBL10680248 | 0.84 | FFAR3 (0.64) | LMNAFFAR3LCKFYNALDH1A1 | |
| Acetic Acid SCHEMBL27652008 | 0.84 | FFAR3 (0.64) | LMNAFFAR3LCKFYNALDH1A1 | |
| Acetic Acid SCHEMBL28907430 | 0.84 | — | — | |
| Acetone SCHEMBL7287347 | 0.84 | — | — | |
| Acetone SCHEMBL27789756 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613961-B1 | Cell containing a DNA molecule comprising a promoter, cytochrome P450 monooxygenase gene and P450 reductase gene; use in detoxifying herbicides, poisons and extrinsic endocrine disruptors; bioremediation | BIO-ORIENTED TECHNOLOGY RESEARCH ADVANCEMENT INSTITUTION (JP) | 2003-09-02 | — | — | US | disclosed |