Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081030 | 0.93 | AR (0.60) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7075370 | 0.91 | KDM4E (0.53) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7075686 | 0.88 | HPGD (0.56) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7080450 | 0.82 | BCHE (0.52) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7081024 | 0.77 | BCHE (0.58) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| 7,2'-Dimethoxyflavone SCHEMBL4285153 | 0.77 | AR (0.81) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7134490 | 0.77 | TNKS (0.57) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7080809 | 0.73 | KDM4E (0.43) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL24913602 | 0.72 | BCHE (0.69) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7075361 | 0.72 | AR (0.65) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610738-B2 | Treatment of Alzheimer's Disease by combining both acetylcholinesterase inhibitory activity and antioxidant activity (by virtue of their carbamoyl and flavonoid pharmacophores) | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2003-08-26 | — | — | US | claimed |