Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | TNKS | O95271 | 2/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 5/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660103 | 0.89 | AR (1.00) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL4443406 | 0.89 | AR (1.00) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL3691018 | 0.89 | MAOB (0.69) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL7075361 | 0.89 | AR (0.65) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL14146408 | 0.88 | ALDH1A1 (0.66) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL253522 | 0.86 | HPGD (0.78) | ARALDH1A1KDM4EMAPTNPC1 | |
| 6-Methoxyflavone SCHEMBL7163227 | 0.86 | AR (0.82) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL4650574 | 0.85 | HPGD (0.81) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL7127255 | 0.85 | KDM4E (0.73) | ARALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL9140634 | 0.85 | KDM4E (0.73) | ARALDH1A1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230074763-A1 | IDENTIFICATION OF HOST-TARGETING MODULATORS OF BACTERIAL UPTAKE AND ASSAY FOR QUANTIFYING INTRACELLULAR BACTERIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-03-09 | — | — | US | claimed |
| US-20210156840-A1 | CRYPTIC ANTIBIOTICS AND METHODS FOR DETECTING BIOACTIVE CRYPTIC METABOLITES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-05-27 | — | — | US | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-12630856-B2 | Identification of host-targeting modulators of bacterial uptake and assay for quantifying intracellular bacteria | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2026-05-19 | — | — | US | disclosed |
| US-12436145-B2 | Cryptic antibiotics and methods for detecting bioactive cryptic metabolites | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2025-10-07 | — | — | US | disclosed |
| US-20230074763-A1 | IDENTIFICATION OF HOST-TARGETING MODULATORS OF BACTERIAL UPTAKE AND ASSAY FOR QUANTIFYING INTRACELLULAR BACTERIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-03-09 | — | — | US | disclosed |
| US-20210156840-A1 | CRYPTIC ANTIBIOTICS AND METHODS FOR DETECTING BIOACTIVE CRYPTIC METABOLITES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-05-27 | — | — | US | disclosed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | NANYANG POLYTECHNIC (SG) | 2015-10-15 | — | — | US | disclosed |
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | NANYANG POLYTECHNIC (SG) | 2015-10-15 | — | — | US | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630856-B2 | Identification of host-targeting modulators of bacterial uptake and assay for quantifying intracellular bacteria | CD14, CLTB, MYADM | AR 4880/4885ALDH1A1 4741/4885KDM4E 4155/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | AR 3549/4885ALDH1A1 2440/4885KDM4E 2309/4885 |
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | TERT, POT1, TERF2 | AR 3657/4885ALDH1A1 2026/4885KDM4E 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.