Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208119 | 1.00 | MAPT (0.38) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL10896691 | 0.83 | MAPT (0.43) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL6058015 | 0.77 | KDM4E (0.44) | MAPTTHRBBLMNOD1HDAC2 | |
| SCHEMBL8915722 | 0.77 | KDM4E (0.44) | MAPTTHRBBLMNOD1HDAC2 | |
| SCHEMBL5261301 | 0.77 | EPHX1 (0.42) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL5261302 | 0.77 | EPHX1 (0.42) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL3045784 | 0.75 | NOD1 (0.46) | MAPTNOD1PLA2G2APLA2G5GPR84 | |
| SCHEMBL3045787 | 0.75 | NOD1 (0.46) | MAPTNOD1PLA2G2APLA2G5GPR84 | |
| SCHEMBL3045780 | 0.75 | NOD1 (0.46) | MAPTNOD1PLA2G2APLA2G5GPR84 | |
| SCHEMBL10488513 | 0.74 | NOD1 (0.48) | MAPTNOD1PLA2G2APLA2G5GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064259-B1 | N,N'-Diacylthiocystines | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | disclosed |