Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Padimate O SCHEMBL29808109 | 0.90 | ALDH1A1 (0.72) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| SCHEMBL7750614 | 0.86 | SIRT2 (0.47) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| Padimate O SCHEMBL28272049 | 0.85 | ALDH1A1 (0.97) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| Padimate A SCHEMBL9452542 | 0.85 | ALDH1A1 (0.60) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| SCHEMBL1961174 | 0.84 | ALDH1A1 (0.90) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| Padimate O SCHEMBL29052074 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| Padimate O SCHEMBL1769139 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| Padimate O SCHEMBL15432 | 0.84 | ALDH1A1 (1.00) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| SCHEMBL5685878 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 | |
| Padimate O SCHEMBL599449 | 0.83 | ALDH1A1 (0.88) | ALDH1A1CYP3A4LMNAHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130155-A1 | Method for producing non-ionic tenside granulates | COGNIS IP MANAGEMENT GMBH (DE) | 2003-07-10 | — | — | US | disclosed |
| US-5750093-A | 33 Lipomelanin sunscreen composition | DUSA PHARMACEUTICALS, INC. (CA) | 1998-05-12 | — | — | US | disclosed |