Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212486 | 0.94 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL6946124 | 0.88 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL12481136 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL12481988 | 0.84 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL6946125 | 0.83 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL31294203 | 0.83 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL25823489 | 0.81 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL14943541 | 0.81 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL14665028 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL13283481 | 0.80 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613934-B1 | Enzymatic partial hydrolysis of a diester of malonic acid | DEGUSSA AG (DE) | 2003-09-02 | — | — | US | disclosed |
| EP-0812819-B1 | Enantiomer-enriched tertiary hydrocarbonrest-substituted malonic acid ester and the preparation | DEGUSSA (DE) | 2001-11-28 | — | — | EP | disclosed |
| EP-0812819-A2 | Enantiomer-enriched tertiary hydrocarbonrest-substituted malonic acid ester and the preparation | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-12-17 | — | — | EP | disclosed |